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Glutathione / NADPH
GSR Glutathione-Recycling Terrain
GSSG-to-GSH recycling context and NADPH dependency boundaries.
Evidence quality visible
No dosing or treatment advice
Terrain context linked
What The Enzyme Does
GSR is represented as glutathione-recycling context. Current content links conceptually to NADPH dependency without adding unapproved graph edges.
- Gene
- Glutathione-disulfide reductase
- External IDs
- MetaboliQ:condition:gsr
What The Variants Change
GSR genotype controls are unavailable until curated variant records and reviewer signoff exist.
No curated variant control is exposed for GSR in Phase 1A.
Downstream Consequences
- GSR may be reviewed as context for reduced-glutathione recycling.
- NADPH dependency is qualitative until graph edges and simulation support are approved.
- The page does not infer oxidative stress burden, supplement need, or treatment response.
Cross-System Connections
Approved seed-graph edges for GSR are pending curation. This page keeps pathway context visible without inventing factor links.
Connected pools: pending approved graph-edge curation